Why Does It Itch When A Wound Heals?

Itching, as stated in the previous post, is caused by the release of a substance known as histamine that stimulates the nerve endings. When tissues become inflamed due to the invasion of bacteria or by trauma such as heat, chemicals or a cut, histamine is released from the cells to the tissues. And, since histamine is a powerful vasodilator, it increases blood flow and the permeability of the blood capillaries in the vicinity of the wound. Apart from this a number white blood cells known as basophils increases during healing. Basophils contains a huge amount of histamine which diffuses into the nearby skin and stimulates the nerve endings, which in turn, leads to itching.